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-1

下面附上一則新聞讓大家了解時事

不少人有脂肪肝困擾,德國一項研究發現,禁食可以幫助對抗脂肪肝。德國赫蒙霍玆慕尼黑衛生與環境研究中心、德國糖尿病研究中心與德國癌症研究中心研究團隊從分子研究角度著手,分析一個人感覺飢餓時的分子變化,結果發現,禁食、沒吃東西的時候,身體會產生一種特殊蛋白,以調節肝臟新陳代謝。

上述研究成果已發表於《EMBO分子醫學》期刊〈EMBOMolecu-larMedicine)。

在現代社會當中,越來越多民眾有體重過重、肥胖等問題,結果就是導致第二型糖尿病等新陳代謝疾病,並對健康造成嚴重影響。若能減少熱量攝取,像進行間歇性禁食,可以幫助新陳代謝恢復正常,不過醫界並不瞭解這種現象的背後機轉。

研究作者德國赫蒙霍玆慕尼黑衛生與環境研究中心糖尿病與癌症研究院主任史黛芬?赫爾奇希與「健康與疾病蛋白新陳代謝」研究組組長亞當?羅斯表示,如果可以了解禁食如何影響身體新陳代謝,或許就可以找到新治療方式。

研究團隊分析禁食所造成的肝細胞基因活動,結果發現當一個人感覺越飢餓,細胞越會產生蛋白分子「GADD45β」,過去研究顯示,這種分子蛋白與細胞修復有關。

研究人員進一步測試發現,「GADD45β」會控制肝臟脂肪酸吸收,老鼠若缺乏這種基因蛋白,很容易產生脂肪肝疾病,當這種蛋白恢復功能,肝超值推臟脂肪含量就會趨於正常,糖分代謝也會改善。研究人員也發現,人體中的「GADD45β」濃度偏低,肝臟就容易囤積脂肪,血糖也很容易上升。



















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