201710090050端粒酶ACRFP關節鏡軟骨再生醫療10促進手術

201007152050ACRFP即將正式在國際曝光 1070膝關節健康促進方案 好文轉寄 將於今年九月在西班牙巴塞隆納舉辦的 第九屆國際軟骨修復學會 (International Cartilage Repair Society, ICRS 2010) 接受了有關 ACRFP 的論文發表(電子海報) ACRFP(關節鏡軟骨再生促進手術), 這我已使用近四年的創新名詞終於被認可,將有機會在國際曝光了!

Arthroscopic Cartilage Regeneration Facilitating Procedure (ACRFP) for OA Knee Shaw-Ruey Lyu, MD, PhD Joint Center Tzu-Chi Dalin General Hospital, Chiayi, Taiwan Abstract Introduction: A novel concept of arthroscopic procedure for the treatment of osteoarthritic (OA) knee was developed based on the conceptualization of a possible pathogenesis process for OA knee featured by focal abrasion phenomenon and soft tissue imbalance. Materials and Methods: From January to December 2005, 571 knees of 367 patients with OA knee have received this procedure. We used Kellgren-Lawrence classification for pre-operative staging.

Pain domain of Knee Society Score (KSS-P) and Knee Injury and Osteoarthritis Outcome Score (KOOS) were used for subjective outcome study.                                        Measurement for the roentgenographic changes of femoral-tibial angle (FTA) and joint space width (JSW) was evaluated for objective outcome study. The mean follow-up period was 38 months (range, 36 to 49).

Results: There were 70 (19%) male and 297 (81%) female and the mean age was 60 years (range, 29 to 82). One hundred and thirty-four knees returned and completed the thorough outcome evaluation. Another 381 knees completed the subjective outcome evaluation by telephone questionnaires. The total follow-up rate was 90.2%. The satisfactory rate for the whole series was 85.5%. The FTA improved from 1.52 (95% confidence interval, 0.84~2.19) to 1.93 (1.21~2.64)(p=0.03). The JSW increased from 2.03 (2.81~3.24) to 2.18 (2.97~3.38)(p=0.01). Conclusion: Arthroscopic cartilage regeneration facilitating procedure is a good option of treatment for OA knee. The beneficial effects of this procedure might be the improvement of the general environment of the knee joint for cartilaginous regeneration after eradication of the possible etiologic factors. 中文簡要: 2005 年,共有 367 位病患的 571 個膝關節因退化性膝關節炎在本中心接受關節鏡軟骨再生促進手術 (ACRFP) 平均追蹤 38 個月,整體滿意度為 85.5%,客觀的放射線檢查,無論是角度、關節間隙,均有統計學意義的改善 事實上,2003 是我第一次在 ICRS 發表對退化性膝關節炎致病機轉的新發現【見:最後一塊拼圖 (16): 大自然的啟示】 轉眼間,七年時光已逝,主流學者仍絡繹不絕的擠進修復被不明原因破壞的軟骨的熱門研究路線, 而我,選擇了人煙稀少的路,企圖自源頭阻斷軟骨的破損, 不自覺,已穿越無數晦暗幽谷,柳暗花明的一刻,似乎已近 ....... 此情此景,讓我憶起學生時期喜歡的一首愛爾蘭民歌: Bushes and Briars Through bushes and briars, I lately found my way, All for to hear the small birds sing, And the lambs to skip and play ........

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